Christina Applegate (born November 25, 1971) is a retired American actress. She gained recognition in the late 1980s for playing Kelly Bundy in the Fox sitcom Married... with Children (1987–1997). Her titular role in the sitcom Jesse (1998–2000), earned her first nomination for the Golden Globe Award for Best Actress – Television Series Musical or Comedy. For her guest role in the NBC sitcom Friends (2002–2003), she won the Primetime Emmy Award for Outstanding Guest Actress in a Comedy Series. She received additional Emmy and Golden Globe nominations for her roles in the television sitcom Samantha Who? (2007–2009), starred in a short-lived sitcom Up All Night (2011–2012), and the dark tragicomedy series Dead to Me (2019–2022). Applegate served as a producer of all three aforementioned projects. Applegate has achieved success in films of varying genres, particularly in comedies such as Don't Tell Mom the Babysitter's Dead (1991), The Big Hit (1998), The Sweetest Thing (2002), Anchorman: The Legend of Ron Burgundy (2004) and Anchorman 2: The Legend Continues (2013), Hall Pass (2011), Vacation (2015), Bad Moms (2016), and Crash Pad (2017). On stage, Applegate received a nomination for the Tony Award for Best Actress in a Musical for her debut performance as the title character in the Broadway musical revival Sweet Charity (2005). After being diagnosed with multiple sclerosis in August 2021, Applegate announced she would step away from appearing on-screen, but would continue doing voice work. She published a memoir in 2026 which became a New York Times Best Seller, where she focused on resilience and self-acceptance.