Rob Lowe at the 2012 Tribeca Film Festival premiere of Knife Fight.

All of the celebrities that drove the All-New Dodge Challenger. Including (from left to right): Snoop Dogg, Audrina Patridge, David Spade, Rob Lowe, Michelle Trachtenberg, Kimberly Williams-Paisley, Brad Paisley, Carmen Electra, Chace Crawford.

Rob Lowe and David Spade are ready for the All-New Dodge Challenger

Rob Lowe in the All-New Challenger

Rob Lowe tells the Dodge Challenger client how fast the Challenger is. It's fast!

Rob Lowe with Challenger

Pearl Harbor, Hawaii (Jun. 30, 2003) -- Actor Rob Lowe, and wife Sheryl Berkoff take photos during a tour of the guided missile destroyer USS Russell (DDG 59) provided by the ships Commanding Officer Cmdr. W. A. Kearns. Lowe and his family are in Hawaii for vacation and were also treated to a tour of Pearl Harbor by Commander, Navy Region Hawaii Rear Adm. Barry McCullough. U.S. Navy photo by Photographer’s Mate 1st Class William R. Goodwin. (RELEASED)

69th Annual Golden Globes Awards.

A Few Good Men at the Haymarket Theatre, London in 2005. A Few Good Men staring Rob Lowe, John Barrowman and Michael Beckley at the Haymarket Theatre, London.

Comic-Con 2010 - TV.com NOW Awards show at Petco Park - Rob Lowe wins an award